Dynamic Light Scattering (DLS) – Dev https://dev.additiveplus.com Thu, 17 Jul 2025 14:17:49 +0000 en-US hourly 1 https://wordpress.org/?v=6.8.5 https://dev.additiveplus.com/wp-content/uploads/cropped-AdditivePlus-Logo-Vertical-Dark-32x32.png Dynamic Light Scattering (DLS) – Dev https://dev.additiveplus.com 32 32 shopengine_activated_templates a:1:{s:6:"single";a:1:{s:4:"lang";a:1:{s:2:"en";a:1:{i:7;a:3:{s:11:"template_id";i:53939;s:6:"status";b:1;s:11:"category_id";s:3:"912";}}}}} Microtrac NANOTRAC WAVE II Nanoparticle Size Analyzer https://dev.additiveplus.com/product/microtrac-nanotrac-wave-ii-nanoparticle-size-analyzer/ Fri, 12 Jul 2024 16:41:16 +0000 https://dev.additiveplus.com/?post_type=product&p=50539 Microtrac’s NANOTRAC WAVE II is a highly flexible Dynamic Light Scattering (DLS) analyzer providing information on particle size, zeta potential, concentration, and molecular weight.

The post Microtrac NANOTRAC WAVE II Nanoparticle Size Analyzer appeared first on Dev.

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Microtrac’s NANOTRAC Wave II / Zeta is a highly flexible Dynamic Light Scattering (DLS) analyzer which provides information on particle size, zeta potential, concentration, and molecular weight. It allows faster measurements with reliable technology, higher precision, and better accuracy. All of this combined into a compact DLS analyzer with a revolutionary fixed optical probe. With the unique and flexible probe design and the use of the Laser Amplified Detection method in the NANOTRAC Wave II / Zeta, the user is able to choose from a wide array of measurement cells that satisfy the needs of any application. This design also allows measurements of samples over a wide concentration range, monomodal or multimodal samples, all without prior knowledge of the particle size distribution. This is made possible through the use of the Frequency Power Spectrum (FPS) method instead of classical Photon Correlation Spectroscopy (PCS).

 

ADVANTAGES

 
  • 180° backscatter DLS setup
  • Stable fixed optics sample interface – no adjustments required
  • Rapid field reversal prevents electro-osmosis
  • Robust mobility calculation as a function of power spectrum ratio
  • High concentration zeta potential measurements
  • Sample concentration and molecular weight determination
  • Universal solvent compatibility
  • Frequence Power Spectrum calculation model instead of PCS
  • Laser Amplified Detection – high signal to noise ratio
  •      


NANOPARTICLE SIZE ANALYZER NANOTRAC WAVE II / ZETA: IDEAL FOR NANOPARTICLE & ZETA POTENTIAL ANALYSIS

The measurement of zeta potential in the NANOTRAC WAVE II particle size analyzer takes advantage of the same Frequency Power Spectrum methodology used for measuring nanoparticle size distributions. The same stable optics sample interface means no adjustments are required. The backscatter and laser amplified detection signals are collected as in the size measurement, and the rapid sequencing of applied electric fields prevents electroosmosis. The optical probe surface is coated to provide electrical contact with the sample. Two probes are used, one to determine the polarity of the particle charge at the slipping plane and one to measure the mobility of the particles in an electric field. Polarity is measured in a pulsed electric field, while mobility is measured in a high frequency sine wave electric field excitation. The zeta cell has two detection probes, on opposite sides, to detect polarity and mobility.

 

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From the linear frequency power spectrum distribution (PSD), the Loading Index (LI), which is proportional to particle concentration, can be calculated. Loading Index values provide a single number for total scattering that can be used to determine particle mobility in microns / sec / volt / cm and particle polarity as + / -, positive or negative. Measuring mobility and zeta potential begins by measuring the PSD and determining the LI with the excitation off. Then the PSD is measured with the high frequency sine wave on and a ratio is taken. Polarity is determined by measuring the LI before and after pulsed DC excitation. A ratio of LI after the excitation divided by LI before excitation of less than one is a positive polarity (concentration decreasing) and a ratio greater than one is negative (concentration increasing) for a positively charged probe surface.

 

Mobility = C × (ratio of [PSD(on) – PSD(off)] / LI(off)

 

Zeta Potential ∝ Mobility

 


NANOPARTICLE SIZE ANALYZER NANOTRAC WAVE II / ZETA: FUNCTIONAL PRINCIPLE

The optical bench of the nanoparticle size analyzer NANOTRAC WAVE II is a probe containing an optical fiber coupled with a Y splitter. Laser light is focused on a volume of sample at the interface of the probe window and the dispersion. The high reflectivity sapphire window reflects a portion of the laser beam back to a photodiode detector. The laser light also penetrates the dispersion and the particle’s scattered light reflects at 180 degrees back to the same detector. The scattered light from the sample has a low optical signal relative to the reflected laser beam. The reflected laser beam mixes with the scattered light from the sample, adding the high amplitude of the laser beam to the low amplitude of the raw scatter signal. This Laser Amplified Detection method provides up to 106 of times the signal to noise ratio of other DLS methods like Photon Correlation Spectroscopy (PCS) and NanoTracking (NT).


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A Fast Fourier Transform (FFT) of the Laser Amplified Detection signal results in a linear frequency power spectrum which is then transformed into logarithmic space and deconvoluted to give the resulting particle size distribution. Combined with Laser Amplified Detection, this frequency power spectrum calculation provides robust calculation of all types of particle size distributions – narrow, broad, mono-modal or multi-modal – with no need for a priori information for algorithm fitting as it is for PCS. The Laser Amplified Detection method used in Microtrac particle analyzers is unaffected by signal aberrations due to contaminants in the sample. Classical PCS instruments need to either filter the sample or create complicated measurement methods to eliminate these signal aberrations.



Iterative Particle Size Calculation from Power Spectrum


iterative-ps-power-spectrum




INTUITIVE USE WITH JUST A FEW CLICKS: DIMENSIONS LS FOR NANOTRAC SERIES



The DIMENSIONS LS software comprises five clearly structured Workspaces for easy method development and operation of the NANOTRAC instrument. Results display and evaluation of multiple analyses are possible in the corresponding workspaces, even during ongoing measurements.


  • Simple method development
  • Clearly structured result presentation
  • Various evaluation options
  • Intuitive workflow
  • Extensive data export
  • Multi-user capability




dimensions-ls-sync-display
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NANOPARTICLE SIZE ANALYZER NANOTRAC WAVE II TYPICAL APPLICATIONS

Versatility is a great strength of Dynamic Light Scattering (DLS). This makes the method suitable for a variety of applications in both research and industry, such as pharmaceuticals, colloids, microemulsions, polymers, industrial minerals, inks and many more.

 

llfeaturespharmaceuticals
llfeaturesemulsions
llfeaturessteel

 

pharmaceuticals

 
  • pharmaceuticals
  • inks
  • life sciences
  • ceramics
  • beverages & food
 

 

  • emulsions

     
    • colloids
    • polymers
    • microemulsions
    • cosmetics
    • chemicals
     
  •  

 

steel

 
  • environment
  • adhesives
  • metals
  • industrial 
  • minerals

The post Microtrac NANOTRAC WAVE II Nanoparticle Size Analyzer appeared first on Dev.

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Microtrac STABINO ZETA Zeta Potential Analyzer https://dev.additiveplus.com/product/microtrac-stabino-zeta-zeta-potential-analyzer/ Fri, 12 Jul 2024 15:22:25 +0000 https://dev.additiveplus.com/?post_type=product&p=50513 Microtrac’s STABINO ZETA is the first choice for zeta potential and colloidal stability accurate determination with very fast titrations performing and replacing classical zeta potential measurements.

The post Microtrac STABINO ZETA Zeta Potential Analyzer appeared first on Dev.

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For the accurate determination of the zeta potential and colloidal stability, the STABINO ZETA is the first choice. It can replace the classical zeta potential measurement and is able to perform very fast titrations. Nowadays, particle surface charge and interface potentials, such as the zeta potential and the streaming potential, are widely used to characterize the stability of suspensions, emulsions and nanoparticles. These parameters have established as a typical measure representing the electrostatic repulsion between particles. The STABINO ZETA has a high resolution and data point density, which allows very fast, precise and reproducible zeta potential measurements. It is possible to measure the zeta potential of particles in the range of 0.3 nm to 300 µm in a concentration range of up to 40 volume percent. Regarding the optimized measurement technology, the STABINO ZETA can measure up to 5 parameters simultaneously and within a few seconds: Zeta potential, streaming potential, conductivity, pH value, and temperature. In combination with our unique NANOTRAC FLEX, the particle size can also be measured as a sixth parameter simultaneously in the same sample.

 

ZETA POTENTIAL ANALYZER STABINO ZETA: FLAWLESS TITRATION

The STABINO ZETA also has a built-in titration function in which all parameters are determined simultaneously at each titration dosing step. The determination of the isoelectric point is one of the titration options and is determined within a few minutes. Your titration options are:

 

PH TITRATION

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POLYELECTROLYTE TITRATION

llproductsstabino-zetatitrationpolyelectrolyte-titrationhl

TITRATION WITH SALTS

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  •  
  • Determination of the isoelectric point
  • Stable pH ranges
  •  
  • Statements about stability
  • Charge density
  • Dispersant optimization
  • Optimization in the formulation of your products
  •  
  • Zeta potential as a function of conductivity



ZETA POTENTIAL ANALYZER STABINO ZETA EXTENSION: IN-SITU SIZE DISTRIBUTION

You are not only interested in the zeta potential of your sample, but also want to determine the particle size distribution? The NANOTRAC FLEX can easily be combined with the STABINO ZETA, i.e. the NANOTRAC FLEX measuring probe can be integrated into the STABINO ZETA measuring cell. This allows the size distribution to be determined either alone or, for example, during a charge titration. Coagulation becomes “visible” in-situ based on particle size, and it is possible to identify the critical agglomeration point of a sample. This is very helpful to evaluate colloidal systems even more precisely.

 

This probe design enables the measurement of samples over a wide concentration range, monomodal or multimodal samples, all without prior knowledge of the particle size distribution. The probe is also very easy and quick to clean between sample measurements of any kind. Additionally, the user can choose from a wide array of measurement cells to satisfy the needs of any application.


ZETA POTENTIAL ANALYZER STABINO ZETA ADVANTAGES


5 MEASUREMENT PARAMETERS AT THE SAME TIME

To determine the quality of your samples, do you need more than just one measurement parameter? The STABINO ZETA provides you with information about the conductivity, zeta potential, streaming potential, temperature and pH of your sample with each measuring point.


"MIX AND MEASURE" - AN ENORMOUS ADVANTAGE

Due to the continuous and rapid mixing of the sample and the titration solution, a charge titration is completed in minutes and additionally prevents sedimentation.

MEASURING
DURING TITRATION

With the STABINO ZETA software you can follow your entire titration or measurement in real time by means of the curve progression, because for each titrated drop you receive a measuring point with all 5 measuring parameters.

ADJUSTED TITRATION SPEED

The titration speed of the STABINO ZETA can be adapted to the reaction speed of your sample. For this purpose, the software offers the possibility to define standard operating procedures (SOPs) as desired.

FAST MEASUREMENT TIME

Most known analytical systems are based on the zeta potential of electrophoresis, where titrations are often too inaccurate and time-consuming. For high sample throughput and thus valuable time savings, the STABINO ZETA has been optimized so that parameters required for quality assurance, for example, can be determined within seconds. For a polyelectrolyte or pH titration, the STABINO ZETA requires only 5 – 15 minutes and can record several hundred data points.


SIMPLE OPERATION

To focus only on the results, the software has been made as easy-to-use as possible. Just pour in 1 – 10 mL sample into the Teflon beaker of the STABINO ZETA, open the software and start the measurement.



ZETA POTENTIAL ANALYZER STABINO ZETA ACCESSORIES

llproductsstabino-zetaaccessoiresmeasuringcell13mlhl
llproductsstabino-zetaaccessoiresmeasuringcell10mlblack
llproductsstabino-zetaaccessoirestemperedmeasuringcellhl
llproductsstabino-zetaaccessoirespistonsethl

 

Measuring cell 1 ml and 3 ml with pestle

 

Measuring cell 10 ml – black –

 

Tempered measuring cell 0 – 90 °C

 

Piston set: 100 µ – 200 µ – 400 µ – 1000 µ – 1200 µ – 1500 µ – 2000 µ – conical



ZETA POTENTIAL ANALYZER STABINO ZETA TYPICAL APPLICATIONS

Versatility is a great strength of Dynamic Light Scattering (DLS). This makes the method suitable for a variety of applications in both research and industry, such as pharmaceuticals, colloids, microemulsions, polymers, industrial minerals, inks and many more.

 

llfeaturespharmaceuticals
llfeaturesemulsions
llfeaturessteel

 

pharmaceuticals

 
  • pharmaceuticals
  • inks
  • life sciences
  • ceramics
  • beverages & food
 

 

  • emulsions

     
    • colloids
    • polymers
    • microemulsions
    • cosmetics
    • chemicals
     
  •  

 

steel

 
  • environment
  • adhesives
  • metals
  • industrial 
  • minerals

The post Microtrac STABINO ZETA Zeta Potential Analyzer appeared first on Dev.

]]>
Microtrac NANOTRAC FLEX Nanoparticle Size Analyzer https://dev.additiveplus.com/product/microtrac-nanotrac-flex-nanoparticle-size-analyzer/ Fri, 12 Jul 2024 12:24:34 +0000 https://dev.additiveplus.com/?post_type=product&p=50471 Microtrac’s NANOTRAC FLEX is a highly flexible nanoparticle size analyzer based on Dynamic Light Scattering (DLS) method.

The post Microtrac NANOTRAC FLEX Nanoparticle Size Analyzer appeared first on Dev.

]]>

Microtrac’s NANOTRAC Flex is a highly flexible nanoparticle size analyzer based on Dynamic Light Scattering (DLS) which provides information on particle size, concentration, and molecular weight. It allows faster measurements with reliable technology, higher precision, and better accuracy. All of this combined into a compact DLS analyzer with a revolutionary fixed optical probe. With the unique and flexible probe design and the use of the Laser Amplified Detection method in the NANOTRAC FLEX, the user is able to choose an appropriate vessel as a measurement cell to satisfy the needs of any application. This design also allows measurements of samples over a wide concentration range, monomodal or multimodal samples, all without prior knowledge of the particle size distribution. This is made possible through the use of the Frequency Power Spectrum (FPS) method instead of classical Photon Correlation Spectroscopy (PCS).

 

ADVANTAGES

 
  • Most flexible Dynamic Light Scattering ever
  • Unique external probe design
  • In situ particle sizing and monitoring
  • 180° backscatter DLS setup
  • Turn any vessel into a sample cell – no consumables required
  • External probe allows dip and measure
  • Universal solvent compatibility
  • Small footprint
  • Frequency Power Spectrum calculation model instead of PCS
  • Laser Amplified Detection – high signal to noise ratio
  •      


FUNCTION PRINCIPLE

The optical bench of the nanoparticle size analyzer NANOTRAC FLEX is a probe containing an optical fiber coupled with a Y splitter. Laser light is focused on a volume of sample at the interface of the probe window and the dispersion. The high reflectivity sapphire window reflects a portion of the laser beam back to a photodiode detector. The laser light also penetrates the dispersion and the particle’s scattered light reflects at 180 degrees back to the same detector. The scattered light from the sample has a low optical signal relative to the reflected laser beam. The reflected laser beam mixes with the scattered light from the sample, adding the high amplitude of the laser beam to the low amplitude of the raw scatter signal. This Laser Amplified Detection method provides up to 106 of times the signal to noise ratio of other DLS methods like Photon Correlation Spectroscopy (PCS) and NanoTracking (NT).


llfunction-3


A Fast Fourier Transform (FFT) of the Laser Amplified Detection signal results in a linear frequency power spectrum which is then transformed into logarithmic space and deconvoluted to give the resulting particle size distribution. Combined with Laser Amplified Detection, this frequency power spectrum calculation provides robust calculation of all types of particle size distributions – narrow, broad, mono- or multi-modal – with no need for a priori information for algorithm fitting as it is for PCS. Microtrac’s Laser Amplified Detection method is unaffected by signal aberrations due to contaminants in the sample. Classical PCS instruments need to either filter the sample or create complicated measurement methods to eliminate these signal aberrations.



ITERATIVE PARTICLE SIZE CALCULATION FROM POWER SPECTRUM

llproductsnanotrac-flexiterativepowerspectrumhl-1




NANOPARTICLE SIZE ANALYZER NANOTRAC FLEX: FLEXIBLE IN SITU MEASUREMENTS

The unique design of the NANOTRAC FLEX probe allows to measure down to only one droplet, thus requiring only a minimum sample volume. The probe also easily fits into a 1.5 ml Eppendorf Tube®. With the NANOTRAC FLEX, every vessel can be used as a measurement vessel, and there is no need for cuvettes of any kind. This makes it possible to use the probe either at line or in line for monitoring the particles’ growth during a reaction. During a reaction, the dispersion is either flowing or stirring. The dispersion motion will obscure the Brownian motion, and a Dynamic Light Scattering (DLS) measurement is normally not possible. To measure in stirring or moving liquids, the FlowGuard can be used. This special cap for the NANOTRAC FLEX probe tip creates an enclosure around the probe, which shields the measurement surface from turbulent flow. An orifice ensures the constant exchange of the sample, while slowing down the stirring movement at the probe interface. This design ensures an accurate particle size distribution that is representative of the suspension outside the enclosure.


This probe design enables the measurement of samples over a wide concentration range, monomodal or multimodal samples, all without prior knowledge of the particle size distribution. The probe is also very easy and quick to clean between sample measurements of any kind. Additionally, the user can choose from a wide array of measurement cells to satisfy the needs of any application.



INTUITIVE USE WITH JUST A FEW CLICKS: DIMENSIONS LS FOR NANOTRAC SERIES



The DIMENSIONS LS software comprises five clearly structured Workspaces for easy method development and operation of the NANOTRAC instrument. Results display and evaluation of multiple analyses are possible in the corresponding workspaces, even during ongoing measurements.


  • Simple method development
  • Clearly structured result presentation
  • Various evaluation options
  • Intuitive workflow
  • Extensive data export
  • Multi-user capability




dimensions-ls-sync-display
-30



NANOPARTICLE SIZE ANALYZER NANOTRAC FLEX TYPICAL APPLICATIONS

Versatility is a great strength of Dynamic Light Scattering (DLS). This makes the method suitable for a variety of applications in both research and industry, such as pharmaceuticals, colloids, microemulsions, polymers, industrial minerals, inks and many more.

 

llfeaturespharmaceuticals
llfeaturesemulsions
llfeaturessteel

 

pharmaceuticals

 
  • pharmaceuticals
  • inks
  • life sciences
  • ceramics
  • beverages & food
 

 

  • emulsions

     
    • colloids
    • polymers
    • microemulsions
    • cosmetics
    • chemicals
     
  •  

 

steel

 
  • environment
  • adhesives
  • metals
  • industrial 
  • minerals

The post Microtrac NANOTRAC FLEX Nanoparticle Size Analyzer appeared first on Dev.

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